Naltrexone Injection: MedlinePlus Drug Information

While the oral formulation will also block opioid receptors, only the long-acting injectable formulation is FDA approved as a medication for OUD. This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects. It’s important to tell your doctor if you have recently taken opioids or opioid-containing medications.

How long do naltrexone side effects last?

Tell your healthcare provider before you take naltrexone if you have any of the following symptoms of opioid withdrawal. This medicine blocks the euphoric and rewarding feeling you get from opioid drugs, including heroin. With the injectable Vivitrol, you may experience reactions at the injection site, including redness, soreness, swelling, and/or bruising. If symptoms persist for more than two weeks or become excessively bothersome, consult your healthcare provider.

  • Always consult your doctor or pharmacist for tailored advice.
  • You may remove weapons or substances that can cause harm if you can do so safely.

The following list may not include all possible serious side effects of the drug. Finally, there’s emerging evidence about the role of LDN in mental health conditions like depression and anxiety. Its mechanism involving endorphins and opioid receptors can influence mood and may offer a new avenue in mental health treatment. If side effects occur, dosage adjustment and titration are often recommended. Always consult your doctor or pharmacist for tailored advice.

naltrexone side effects

Get Naltrexone at Confidant Health!

  • Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use.
  • When starting Naltrexone, some patients experience mild to moderate side effects, particularly in the first few days or weeks.
  • đź’ˇ This article is for informational purposes only and does not constitute medical advice.
  • Learn more about some of the side effects that naltrexone oral tablet may cause.

This occurs because naltrexone blocks opioid receptors, preventing opioids from exerting their effects and abruptly causing withdrawal symptoms. Drinking alcohol can also produce pleasurable and rewarding feelings. These feelings partly occur because alcohol increases your body’s production of endorphins. Endorphins are your body’s natural pain-relieving and “feel-good” chemicals.

  • Naltrexone blocks opioid receptors, preventing the high from opioids and reducing alcohol cravings.
  • The pill form of naltrexone (ReVia, Depade) can be taken at 50 mg once per day.
  • Naltrexone is a medication used to treat opioid use and alcohol use disorders in adults, as part of a comprehensive management program.

How Naltrexone Helps with Alcohol Use Disorder

Muscle pain and joint pain were common side effects reported in studies of naltrexone. These side effects may cause discomfort in various muscles or joints throughout your body. If you have bothersome or long-lasting digestive side effects during naltrexone treatment, talk with your doctor. They can suggest ways to manage symptoms, such as nausea, constipation, and diarrhea. If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away.

Naltrexone may cause mild side effects other than those listed above. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. Ask your doctor or pharmacist any questions you have about naltrexone. There are certain considerations to keep in mind before starting naltrexone. If you have questions about naltrexone and naltrexone side effects side effects, talk with your doctor.

naltrexone side effects

This contributes to immune modulation, a regulatory effect on the immune system. The result is a decrease in inflammation, a key feature of autoimmune diseases. While LDN shows promise in several areas, the future holds potential for even more applications, like its use in neurological disorders such as Parkinson’s and Alzheimer’s disease. The scientific community is keen on establishing its long-term safety and efficacy.

Do not take naltrexone unless it has been prescribed to you by a healthcare provider. Never share this medicine with anyone else, especially someone who is using opioids. Naltrexone causes withdrawal symptoms in people who are using opioids.

More Common Side Effects of Naltrexone

Symptoms of liver toxicity include jaundice, fatigue, and abdominal pain. Regular liver function tests are recommended to ensure any potential issues are caught early. Naltrexone can affect liver function, particularly at higher doses. Elevated liver enzymes are mostly mild and self-limiting but can indicate liver damage.

Strategies to Enhance Patient Tolerance of Oral Naltrexone

naltrexone side effects

Also, naltrexone has other effects on other receptor systems that can vary between people. One set of adverse effects is that weirdness, that feeling weird, high, intoxicated. Ones—gastrointestinal—where people have nausea, they have diarrhea, they’re queasy all the time. That is probably due to some of the mu effects, as well as the kappa alcoholism symptoms effects of the drug. Stuff, you may be able to affect that by either increasing or decreasing the dose and waiting.

Differentiating Side Effects from Opioid Withdrawal Symptoms

Tell them about all prescription, over-the-counter, and other drugs you take. Also, tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. Opioids are powerful, addictive drugs that have high risks of misuse and dependence. Naltrexone is often confused with naloxone, an opioid overdose reversal medication. Although these medications are both opioid antagonists, they serve very different purposes in people who use opioids.

Stem cell therapy for liver disease offers a new hope for the increasing number of patients affected by this condition, which leads to over 33,500 deaths annually in the U.S. This innovative treatment addresses the limitations of past therapies, providing a more accessible and effective option for improving patients’ health and quality of life. There are numerous online forums and support groups where patients share their LDN experiences. These communities can be valuable, but remember, they are not a substitute for professional medical advice. A clear understanding of naltrexone side effects is essential. Common side effects include nausea, headaches, and dizziness.

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